Customized Scaffold Design Based on Natural Peripheral Nerve Fascicle Characteristics for Biofabrication in Tissue Regeneration

Figure 4

A biofabrication model that mimics the microstructure of peripheral nerve fasciculus was designed based on the three-dimensional database: In scenarios of patients with nerve defects, a nerve graft was designed and customized to the nerve defects. (a) Distal and proximal part of the nerve defect. (b) Differences in the fascicular structure of the distal and proximal part of the nerve defect. (c) The nerve graft was designed according to the three-dimensional database of nerve fasciculus. (d, e, and f) Simulation of the matching between the nerve graft and nerve defect.

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