A Novel Clinical Six-Flavoprotein-Gene Signature Predicts Prognosis in Esophageal Squamous Cell Carcinoma

Table 3

Identities of flavoproteins and their interacting proteins in the prognostic expression signature and their univariate Cox association with prognosis.

Ensembl ID	Gene symbol	Gene description	Coefficient^a	value^a	Gene expression level association with prognosis	Chromosome location
ENSG00000115159	GPD2	Glycerol-3-phosphate dehydrogenase 2	−0.77	0.01	Low	2 : 156435290–156613735 : 1
ENSG00000119943	PYROXD2	Pyridine nucleotide-disulphide oxidoreductase domain 2	0.28	0.00	High	10 : 98383565–98415184 : −1
ENSG00000085733	CTTN	Cortactin	0.33	0.00	High	11 : 70398404–70436584 : 1
ENSG00000137563	GGH	Gamma-glutamyl hydrolase	−0.39	0.01	Low	8 : 63015079–63039171 : −1
ENSG00000197122	SRC	Non-receptor tyrosine kinase	0.54	0.02	High	20 : 37344685–37406050 : 1
ENSG00000213463	SYNJ2BP	Synaptojanin 2 binding protein	0.48	0.02	High	14 : 70366496–70417061 : −1

^aDerived from the univariable Cox regression analysis in the training set.