Bioinformatics Analysis Identified Key Molecular Changes in Bladder Cancer Development and Recurrence

Figure 1

4211 differentially expressed genes (DEGs) were found by comparing 58 normal tissues surrounding cancer and 165 primary bladder cancer samples, and 410 DEGs were found by comparing 165 primary bladder cancer and 23 recurrent samples. There were 1657 and 258 upregulated DEGs and 2514 and 152 individually downregulated DEGs for each group. 91 and 57 overlap genes were found in up- and downregulation genes.