Effects of Proanthocyanidins on Arsenic Methylation Metabolism and Efflux in Human Hepatocytes L-02
Figure 3
Effect of proanthocyanidins (PC) on primary methylation index (PMI) and secondary methylation index (SMI) in L-02 cells exposed by arsenic trioxide (ATO). The PMI (a) and SMI (b) are shown. Values are means (n=3 for each group), with standard deviations represented by vertical bars. Indicating significant difference from ATO exposure group with 24h at P<0.05. Indicating significant difference from PC (10mg/L)-treated group with 24h at P<0.05. Indicating significant difference from PC (25mg/L)-treated group with 24h at P<0.05. Indicating significant difference from ATO exposure group with 48h at P<0.05. Indicating significant difference from PC (10mg/L)-treated group with 48h at P<0.05. Indicating significant difference from PC (25mg/L)-treated group with 48h at P<0.05.