Effects of Proanthocyanidins on Arsenic Methylation Metabolism and Efflux in Human Hepatocytes L-02

Figure 6

Analysis of the correlation between glutathione (GSH)/arsenic (+3 oxidation state) methyltransferase (AS3MT)/S-adenosyl methionine (SAM) and arsenic metabolites contents in arsenic trioxide (ATO) infected L-02 cells by proanthocyanidins (PC) intervention. The horizontal and vertical coordinates of each data point referred to the contents of GSH, AS3MT, SAM, and corresponding methyl arsenic under the intervention of different doses of PC. MMA, monomethylated arsenic; DMA, dimethylated arsenic.