Quantitative Proteomic Analysis Reveals the Deregulation of Nicotinamide Adenine Dinucleotide Metabolism and CD38 in Inflammatory Bowel Disease

Figure 1

Summary of proteomics analysis of NC, CD, and UC using TMT quantitation method. (a) Venn diagram showing proteins identified across 3 TMT experiments, from which 4786 commonly identified proteins were used for downstream analyses. (b) Overall differences of proteome between NC, CD, and UC were summarized by PCA plot. (c) Heat map representation of abundance profiles of all 4786 proteins in all samples. Color shade correlates with relative protein abundances across each row (red/green for upregulation/downregulation).

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