Quantitative Proteomic Analysis Reveals the Deregulation of Nicotinamide Adenine Dinucleotide Metabolism and CD38 in Inflammatory Bowel Disease

Figure 5

CD38 is increased in IBD patients. (a) Western blot analysis of CD38 expression in control and UC patients (N=3 per group). (b) Western blot analysis of CD38 expression in 3 matched pairs of inflamed (I) and noninflamed (NI) UC tissues. (c) Western blot analysis of CD38 expression in control and CD patients (N=3 per group). (d) Western blot analysis of CD38 expression in 3 matched pairs of inflamed (I) and noninflamed (NI) CD tissues. (e) Expression of CD38 by IHC (original magnification×100). (f) Immunofluorescence staining of DAPI (blue), CD38 (green), and F4/80 (red) in control, UC, and CD patients (N=3 per group) (original magnification, ×200). CD, Crohn’s disease; UC, ulcerative colitis.

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