Quantitative Proteomic Analysis Reveals the Deregulation of Nicotinamide Adenine Dinucleotide Metabolism and CD38 in Inflammatory Bowel Disease

Table 3

Expression of proteins involved in NAD metabolism and signaling pathway within the proteomic results.

UniProt accession	Protein	p value	Fold change	Unique	GI related or not
			IBD/Con	peptides	not
P36222	CD38	0.0030	2.49	9	not
O95544	NADK	0.0768	1.43	5	not
Q4G0N4	NADK2	0.0183	0.82	6	not
Q6IA69	NADSYN1	0.7181	0.97	3	not
C9JF35	NAMPT	0.0084	1.77	14	not
Q6XQN6	NAPRT	0.3029	0.88	14	not
Q9HAN9	NMNAT1	0.112	0.87	3	not
Q96T66	NMNAT3	0.1096	0.79	2	not
P40261	NNMT	0.0013	1.73	6	not
Q13423	NNT	0.0023	0.79	4	yes
Q8TCD5	NT5C	0.1245	0.83	6	not
P49902	NT5C2	0.4623	0.94	4	not
Q9H0P0	NT5C3A	0.0288	0.67	7	not
P21589	NT5E	0.7597	0.92	3	not
Q9BQG2	NUDT12	0.0875	0.82	2	not
P00491	PNP	0.0131	1.34	10	not
Q15274	QPRT	0.1998	1.47	4	not
Q96EB6	SIRT1	0.1482	1.19	2	not
Q8IXQ6	PARP9	0.0038	1.53	9	not
Q460N5	PARP14	0.0013	1.52	12	yes
Q00653	NFKB2	0.0446	1.65	4	not
P19838	NFKB1	0.7749	1.02	11	not

IBD, inflammatory bowel disease. Con, control. GI, gastrointestinal.