Transient Elastography and Ultrasonography: Optimal Evaluation of Liver Fibrosis and Cirrhosis in Patients with Chronic Hepatitis B Concurrent with Nonalcoholic Fatty Liver Disease
Table 1
Patients’ characteristics.
Characteristic
Standard Value (Range)
Patients (n=94)
Mean age (years)
NA
36.90±8.17
Male gender (n, %)
NA
85 (90.4%)
Body mass index (BMI) (kg/m2)
NA
24.20±2.68
BMI ≥ 25 (n, %)
NA
36 (37.9%)
Aspartate aminotransferase (IU/L)
15-40
29 (15-128)
Alanine aminotransferase (IU/L)
3-35
40.5 (9-173)
Total bilirubin (umol/L)
4-23.9
12.7 (5.6-32.5)
Albumin (g/L)
36-51
45.5 (36.2-51.6)
g-Glutamyltransferase (IU/L)
10-60
32.5 (12-283)
Alkaline phosphatase (IU/L)
45-125
72.5 (33-207)
Platelets count (103/mm3)
100–350
200.43±54.87
Prothrombin time activity (%)
70–120
96.18±11.68
Fasting glucose (mmol/L)
3.9-6.1
4.90 (3.64-8.61)
Fasting glucose ≥5.6 mmol/L (n, %)
≥5.6
23 (24.5%)
Total cholesterol (mmol/L)
3.1-5.7
4.78±0.84
Triglyceride (mmol/L)
0.34-1.92
1.19 (0.39-4.89)
Triglyceride ≥ 1.7 mmol/L (n, %)
≥1.7
22 (23.4%)
HDL-cholesterol (mmol/L)
0.78-2.00
1.15±0.23
Reduced HDL-cholesterol (mmol/L) (n, %)
<1.03 in men <1.29 in women
29 (30.8%)
LDL-cholesterol (mmol/L)
2.07-3.10
3.17±0.83
Elevated LDL-cholesterol (n, %)
>3.10
52 (55.3%)
HBeAg positive (n, %)
>1
38 (40.4%)
HBV-DNA (log10 IU/mL)
<20 IU/mL
4.83 (1.54-8.68) ∗
Ultrasonography score
4/5
NA
0/28
6/7
NA
29/18
8/≥9
NA
11/8
Fibrosis score (METAVIR)
F0 (n, %)
NA
19 (20.2%)
F1 (n, %)
NA
28 (29.7%)
F2 (n, %)
NA
16 (17.0%)
F3 (n, %)
NA
17 (18.1%)
F4 (n, %)
NA
14 (15.0%)
Hepatic steatosis
≥5%
NA
90 (95.7%)
34-66%
NA
3 (3.2%)
>66%
NA
1 (1.1%)
Unless otherwise indicated, data were expressed as means ± standard deviations or medians and ranges. ∗Eleven patients had undetectable HBV-DNA loads. HDL=high density lipoprotein; LDL= low-density lipoprotein; NA=not applicable.
