Trans-Cinnamaldehyde Inhibits IL-1β-Stimulated Inflammation in Chondrocytes by Suppressing NF-κB and p38-JNK Pathways and Exerts Chondrocyte Protective Effects in a Rat Model of Osteoarthritis

Figure 6

TCA reduced the mRNA expression of MMP-1, MMP-3, MMP-13, ADAMTS-4, and ADAMTS-5 in IL-1β-stimulated chondrocytes. The mRNAs were assessed by RT-qPCR. (a) MMP-1. (b) MMP-2. (c) MMP-3. (d) MMP-9. (e) MMP-13. (f) ADAMTS-4. (g) ADAMTS-5. P<0.05.

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