Modulation of Corneal FAK/PI3K/Akt Signaling Expression and of Metalloproteinase-2 and Metalloproteinase-9 during the Development of Herpes Simplex Keratitis
Table 4
Comparison of relative expression levels of p-FAK, FAK, p-PI3K, PI3K, p-Akt, Akt, MMP-2, and MMP-9 in cornea at each time point (X±s).
Time point
p-FAK
FAK
p-PI3K
PI3K
p-Akt
Akt
MMP-2
MMP-9
0d
0.04±0.01
0.54±0.02
0.04±0.01
0.63±0.02
0.04±0.01
0.63±0.00
0.04±0.00
0.06±0.04
2d
0.26±0.1
0.56±0.02
0.24±0.0
0.64±0.01
0.29±0.0
0.62±0.01
0.45±0.1
0.33±0.1
7d
0.19±0.1
0.55±0.02
0.09±0.0
0.64±0.01
0.14±0.0
0.61±0.00
0.24±0.1
0.20±0.1
14d
0.54±0.0
0.57±0.02
0.53±0.0
0.67±0.00
0.47±0.0
0.64±0.01
0.74±0.0
0.50±0.1
28d
0.35±0.1
0.57±0.01
0.39±0.0
0.66±0.01
0.35±0.0
0.63±0.00
0.56±0.0
0.42±0.1
F
15.51
1.51
123.38
8.73
119.07
10.14
25.31
5.84
P
<0.05
>0.05
<0.05
>0.05
<0.05
>0.05
<0.05
<0.05
Note. compared with 0d; compared with 14d (one-way ANOVA, LSD-t test).
