Clinical Study

High-Flow Nasal Cannula and Mandibular Advancement Bite Block Decrease Hypoxic Events during Sedative Esophagogastroduodenoscopy: A Randomized Clinical Trial

Table 1

Patient and endoscopic exam characteristics.

Groups newstandard (n=51)HFNC (n=50)MA bite block (n=51)

Age (years)51.56 ± 12.5246.65 ± 15.3751.07 ± 11.960.130
Sex (Male n/ Female n)22 / 2919 / 3119 / 320.804
ASA (I n/ II n)22 / 297 / 4320 / 310.003
Weight (kg)63.89 ± 11.8562.46 ± 13.2061.26 ± 14.560.605
Height (cm)162.57 ± 8.84163.44 ± 6.74161.61 ± 8.300.522
BMI (kg/m2)23.44 ± 3.5822.51 ± 4.1922.90 ± 3.580.466
STOP-Bang risk (low n/mod n/high n)21/17/1326/13/1132/12/60.208

Mean time to reach MOAA/S < 21.77 ± 0.762.12 ± 1.542.04 ± 1.020.279
Exam time5.83 ± 2.335.96 ± 1.696.47 ± 2.120.263
BIS75.29 ± 14.2778.08 ± 14.8475.66 ± 16.990.616
Propofol TCI Ce1.05 ± 0.411.45 ± 0.511.29 ± 0.590.001

Data are represented as mean ± standard deviation.
ASA: American Society of Anesthesiologists classification, BMI: body mass index, STOP-Bang: STOP-Bang questionnaire; MOAA/S: Modified Observer’s Assessment of Alertness/Sedation; BIS: Bispectral index; Propofol TCI Ce: effect site concentration for propofol target controlled infusion; HFNC: high-flow nasal cannula; MA: mandibular advancement.