A Six-Gene Signature Predicts Survival of Adenocarcinoma Type of Non-Small-Cell Lung Cancer Patients: A Comprehensive Study Based on Integrated Analysis and Weighted Gene Coexpression Network

Figure 8

The relative levels of RRAGB, RSPH9, RPS6KL1, RXFP1, RRM2, and RTL1 in NSCLC adenocarcinoma. (a) Compared with the normal control, RRAGB, RSPH9, and RXFP1 mRNA levels were significantly decreased and RPS6KL1, RTL1, and RRM2 mRNA levels were significantly increased in NSCLC of TCGA-LUAD. (b) The expression levels of RRAGB, RSPH9, RPS6KL1, and RXFP1 were significantly lower and RTL1 and RRM2 mRNA levels were significantly higher in the high-risk group than those in the low-risk group of TCGA-LUAD. (c) The expression levels of RRAGB, RSPH9, RPS6KL1, RXFP1, and RTL1 were significantly lower and RRM2 mRNA levels was significantly higher in the high-risk group than those in the low-risk group in NSCLC adenocarcinoma of GSE11969.

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