Rapid Enkephalin Delivery Using Exosomes to Promote Neurons Recovery in Ischemic Stroke by Inhibiting Neuronal p53/Caspase-3

Figure 6

Effect of tar-exo-enkephalin on neuronal disorders in tMCAO. After injection with exo-enkephalin in tMCAO at 1 week and 3 weeks, the neurological scores both improve, as well as the increasing of holding angle in the inclined board test. Tar-exo-enkephalin also inhibited the ischemic injuries. n=10 per group. Results are expressed as mean ± SD, and #P< 0.05, and ##P< 0.01.

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