Gene Expression Profiles of Peripheral Blood Monocytes in Osteoarthritis and Analysis of Differentially Expressed Genes

Table 1

The top 30 up- and downregulated DEGs in peripheral blood mononuclear cells of patients with OA.

Gene symbol upregulated expression	Accession number	value	Fold change
RPL38	NM_000999	5.30E − 05	1.70
PPP3CA	NM_000944	7.40E − 05	1.42
TROVE2	NM_001042369	8.10E − 05	1.28
PRPF40A	NM_017892	9.50E − 05	1.41
CEP350	NM_014810	1.18E − 04	1.52
TROVE2	NM_001042369	1.47E − 04	1.35
CEP350	NM_014810	1.59E − 04	1.41
MRPS31	NM_005830	1.65E − 04	1.33
RAB11A	NM_001206836	1.84E − 04	1.44
ZC3H14	NM_001160103	1.85E − 04	1.35
USP12	NM_182488	1.96E − 04	1.38
GTF2H5	NM_207118	2.32E − 04	1.37
ITPR1	NM_001099952	2.45E − 04	1.35
MTF2	NM_001164391	2.54E − 04	1.44
CLCN3	NM_001243372	2.59E − 04	1.31
C6orf62	NM_030939	2.94E − 04	1.56
MOSPD1	NM_019556	3.25E − 04	1.25
PIGF	NM_002643	3.54E − 04	1.43
PREPL	NM_001042385	3.89E − 04	1.39
THUMPD1	NM_017736	4.08E − 04	1.37
CEP57	NM_001243776	4.13E − 04	1.41
PHACTR2	NM_001100164	4.41E − 04	1.43
ADAMTS10	NM_001110	4.52E − 04	1.28
E2F3	NM_001243076	4.53E − 04	1.41
ING3	NM_019071	4.71E − 04	1.49
MYCBP2	NM_015057	4.75E − 04	1.32
USP7	NM_003470	4.90E − 04	1.39
PHKB	NM_000293	5.07E − 04	1.28
MED1	NM_004774	5.19E − 04	1.41
NDUFA5	NM_005000	5.78E − 04	1.51
IKZF1	NM_001220765	1.36E − 04	1.56
C7orf43	NM_018275	1.87E − 04	1.29
RAB3D	NM_004283	2.51E − 04	1.33
CDV3	NM_001134422	2.59E − 04	1.25
FRS3	NM_006653	2.64E − 04	1.23
ARF3	NM_001659	3.46E − 04	1.34
LMO4	NM_006769	3.64E − 04	1.22
RING1	NM_002931	4.61E − 04	1.23
NADK	NM_001198993	5.82E − 04	1.36
MTMR3	NM_001013676	5.99E − 04	1.28
PTGES2	NM_001256335	6.04E − 04	1.34
MAX	NM_001271068	6.32E − 04	1.47
LOC100996752	NM_019094	6.73E − 04	1.22
MARS	NM_004990	8.23E − 04	1.21
SIGLEC7	NM_001277201	8.49E − 04	1.24
DUSP3	NM_004090	8.91E − 04	1.39
TNFAIP2	NM_006291	9.11E − 04	1.38
MAT2A	NM_005911	9.78E − 04	1.41
BRD2	NM_001113182	1.06E − 03	1.44
MED12	NM_005120	1.23E − 03	1.23
SLC25A28	NM_031212	1.26E − 03	1.24
STX16	NM_001001433	1.44E − 03	1.39
USP21	NM_001014443	1.50E − 03	1.26
TM9SF4	NM_014742	1.55E − 03	1.39
CBFB	NM_001755	1.57E − 03	1.28
GGA2	NM_015044	1.60E − 03	1.21
POLG	NM_001126131	1.61E − 03	1.34
YKT6	NM_006555	1.68E − 03	1.25
CLASRP	NM_001278439	1.75E − 03	1.28
RCN3	NM_020650	1.94E − 03	1.21