Curcumin Induces Neural Differentiation of Human Pluripotent Embryonal Carcinoma Cells through the Activation of Autophagy

Figure 6

Schematic illustration of the effects of curcumin on neural differentiation. Curcumin induced NTERA2 cells toward neuronal cell fate by activating autophagy in an ROS-dependent manner. This emphasized the feasibility of using NTERA2 cells as a cell-based platform for human brain development study and neurogenesis compound screening.