Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide

<div>Effect of diallyl trisulfide (DATS) on Srx protein expression, MDA level and H<sub>2</sub>O<sub>2</sub> level in BGC823 cells. (A) Western blot of Srx after 0, 2, and 4 h of 5 <i>μ</i>g/ml DATS treatment of BGC823 cells. (B) Immunofluorescence analysis of Srx showing the downregulation of Srx after 2 h of 5 <i>μ</i>g/ml DATS treatment. (C) MDA level after 0, 2, and 4 h of 5 <i>μ</i>g/ml DATS treatment of BGC823 cells. (D) H<sub>2</sub>DCFDA in BGC823 cells. a, control; b, 5 <i>μ</i>g/ml DATS incubation for 2 h.</div>

BioMed Research International

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Figure 3

Figure 3: Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide 