Arsenic Trioxide Suppresses Tumor Growth through Antiangiogenesis via Notch Signaling Blockade in Small-Cell Lung Cancer

Figure 4

As₂O₃ disrupted the tube formation ability of HUVECs in vitro. (a) The tube formation capacity of HUVECs transfected with Dll4 overexpression lentiviruses or NC lentiviruses with or without As₂O₃ treatment. Scale bars, 200 μm. (b) The tube formation capacity of HUVECs transfected with Notch1 siRNA lentiviruses or NC lentiviruses with or without As₂O₃ treatment. Scale bars, 200 μm. (c, d) Quantification of cord formation. Columns, mean; error bars, SD. , .

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