BioMed Research International / 2019 / Article / Fig 5

Research Article

Arsenic Trioxide Suppresses Tumor Growth through Antiangiogenesis via Notch Signaling Blockade in Small-Cell Lung Cancer

Figure 5

The effect of As2O3 treatment on the regulation of the expression of the Notch pathway-related factors in HUVECs. (a) Western blot analysis to reveal the expression of Dll4, Notch1, and Hes1 proteins in the HUVECs transfected with Dll4 overexpression lentiviruses or NC lentiviruses with or without As2O3 treatment. (b) The expression of Dll4, Notch1, and Hes1 proteins in the HUVECs transfected with Notch1 siRNA lentiviruses or NC lentiviruses with or without As2O3 treatment.

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