Jiedu Granule Combined with Transcatheter Arterial Chemoembolization and Gamma Knife Radiosurgery in Treating Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Table 1
Main procedure-related clinical adverse events by CTCAE grades in both groups.
CTCAE
Group
Grade 1
Grade 2
Grade 3
Grade 4
Grade 5
All grades
P value
Abdominal pain
TACE-GKR (n=94)
10(10.64)
1(1.06)
0
0
0
11(11.7)
0.430
Jiedu plus TACE-GKR (n=96)
8(8.33)
0
0
0
0
8(8.33)
Anorexia
TACE-GKR (n=94)
12(12.77)
14(14.89)
4(4.26)
0
0
30(31.91)
0.301
Jiedu plus TACE-GKR (n=96)
8(8.33)
15(15.63)
1(1.04)
0
0
24(25)
Ascites
TACE-GKR (n=94)
3(3.19)
1(1.06)
0
0
0
4(4.26)
0.991
Jiedu plus TACE-GKR (n=96)
2(2.08)
2(2.08)
0
0
0
4(4.17)
Constipation
TACE-GKR (n=94)
3(3.19)
1(1.06)
0
0
0
4(4.26)
0.967
Jiedu plus TACE-GKR (n=96)
4(4.17)
0
0
0
0
4(4.17)
Dermatitis
TACE-GKR (n=94)
12(12.77)
4(4.26)
0
0
0
16(17.02)
0.728
Jiedu plus TACE-GKR (n=96)
14(14.58)
1(1.04)
0
0
0
15(15.63)
Fatigue
TACE-GKR (n=94)
14(14.89)
15(15.96)
0
0
0
29(30.85)
0.362
Jiedu plus TACE-GKR (n=96)
16(16.67)
9(9.38)
0
0
0
25(26.04)
Fever
TACE-GKR (n=94)
21(22.34)
4(4.26)
0
0
0
25(26.6)
0.755
Jiedu plus TACE-GKR (n=96)
17(17.71)
6(6.25)
0
0
0
23(23.96)
Ileus
TACE-GKR (n=94)
6(6.38)
0
0
0
0
6(6.38)
0.144
Jiedu plus TACE-GKR (n=96)
2(2.08)
0
0
0
0
2(2.08)
Nausea/vomiting
TACE-GKR (n=94)
24(25.53)
5(5.32)
0
0
0
29(30.85)
0.143
Jiedu plus TACE-GKR (n=96)
19(19.79)
1(1.04)
1(1.04)
0
0
21(21.88)
Pneumonitis
TACE-GKR (n=94)
1(1.06)
3(3.19)
0
0
0
4(4.26)
0.401
Jiedu plus TACE-GKR (n=96)
0
2(2.08)
0
0
0
2(2.08)
CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events. GKR: gamma knife radiosurgery. TACE: transarterial chemoembolization.
