Biochemical Changes in Blood of Patients with Duchenne Muscular Dystrophy Treated with Granulocyte-Colony Stimulating Factor

Table 1

The hematological parameters in children and adolescents with Duchenne muscular dystrophy during treatment with granulocyte-colony stimulating factor.

Measurement		Red blood cells (4.5-5.5 10'6/μl, normal range)			Hemoglobin (12.0 -15.5 g/dl, normal range)
		Average	SD	P value	Average	SD	P value
Cycle 1	1	5.33	1.14	NS	13.82	0.83	NS
	2	5.11	0.33		13.83	0.83
Cycle 2	1	5.10	0.34	NS	13.93	0.96	NS
	2	5.18	0.29		14.24	0.87
Cycle 3	1	5.00	0.29	NS	13.57	0.96	NS
	2	5.04	0.30		13.7	1.08
Cycle 4	1	5.12	0.36	NS	13.82	1.13	NS
	2	5.14	0.36		13.78	0.87
Cycle 5	1	5.14	0.29	NS	13.86	0.86	NS
	2	5.09	0.31		13.83	1.00
Measurement		Platelets (140.0-450.0 10'3/μl, normal range)			Leucocyte (4.0-12.0 10'3/μl, normal range)
		Average	SD	P value	Average	SD	P value
Cycle 1	1	327.89	87.96	NS	7.06	2.05	<0.001
	2	322.00	63.33		29.53	13.23
Cycle 2	1	381.88	106.84	NS	7.32	2.58	<0.001
	2	348.75	63.62		31.69	13.38
Cycle 3	1	347.68	79.61	NS	6.66	1.89	<0.001
	2	354.74	77.61		32.66	12.17
Cycle 4	1	327.11	69.76	NS	7.22	2.22	<0.001
	2	328.11	66.24		27.05	10.00
Cycle 5	1	334.88	60.52	NS	7.16	2.51	<0.001
	2	319.00	70.77		24.23	10.59