Biochemical Changes in Blood of Patients with Duchenne Muscular Dystrophy Treated with Granulocyte-Colony Stimulating Factor

Table 3

The parameters of coagulation system in children and adolescents with Duchenne muscular dystrophy during treatment with granulocyte-colony stimulating factor.

Measurement		Prothrombin time (10.4-14sec)		P	Prothrombin index (80-120%)		p	Kaolin-kephalin time (21.1-32sec)		p	Fibrinogen (200-360mg/dl)		p
		Mean	SD		Mean	SD		Mean	SD		Mean	SD
Cycle 1	1	10.88	0.83	NS	112.26	8.70	NS	25.36	3.10	NS	321.80	413.20	NS
	2	10.99	1.16		110.95	11.27		24.77	2.02		316.21	414.31
Cycle 2	1	10.86	0.68	NS	111.59	6.73	NS	25.38	2.54	NS	228.10	59.00	NS
	2	10.9	0.97		112.78	7.83		24.98	2.29		218.80	58.41
Cycle 3	1	11.04	0.67	NS	109.56	6.18	NS	25.54	2.39	NS	245.90	99.43	NS
	2	11.18	0.77		109.06	7.75		25.53	1.87		234.10	62.90
Cycle 4	1	10.74	0.62	NS	112.79	6.29	NS	25.86	2.25	NS	211.80	50.90	NS
	2	10.91	0.71		111.16	6.80		25.73	2.99		223.00	60.62
Cycle 5	1	10.79	0.84	NS	112.59	8.45	NS	26.37	2.49	NS	222.11	57.00	NS
	2	10.86	0.47		105.65	24.83		26.07	2.77		202.80	33.81

NS, nonsignificant.