N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor

Figure 8

NAC can inhibit the release of chemokines in cisplatin injured mice. Real-time PCR showing relative renal mRNA levels of TNF-α(a), IL-1β(b), ICAM-1(c), IL-6(d), CXCL1(e), CXCL6 (f), IL-8 (g), and MIP-1(h) in each group in kidney. The values are presented as the means±SEM, n =8. P < 0.05; P < 0.01.

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