Research Article

Silymarin Ameliorates Acrylamide-Induced Hyperlipidemic Cardiomyopathy in Male Rats

Table 2

Effect of silymarin on lipid profile in rats treated with acrylamide.

Experimental groupsTC (mg/dl)TGs (mg/dl)HDL-C (mg/dl)LDL-C (mg/dl)VLDL-C (mg/dl)

Control86.20c ± 0.6658.80c ± 1.1147.20a ± 0.9735.40c ± 0.9811.08c ± 0.35
AA174.60a ± 1.21133.40a ± 0.8133.20b ± 0.97107.20a ± 0.8626.12a ± 1.09
SIL84.60c ± 1.0359.60c ± 0.7547.0a ± 0.9535.20c ± 0.4911.48c ± 0.43
AA+SIL102.80b ± 0.7385.20b ± 0.8635.0b ± 1.6456.60b ± 1.2917.80b ± 0.58
One-way ANOVA F ()2064.68 (<0.001*)1529.98 (<0.001*)41.52 (<0.001*)1278.43 (<0.001*)108.31 (<0.001*)

Data are expressed as the mean ± SE of five rats/group. Means within the same column with different superscript letters are significant. *: Statistically significant at . TC: total cholesterol, TG: triglycerides, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, and VLDL-C: very-low-density lipoprotein cholesterol.