Research Article

LC-MS/MS Analysis and Hepatoprotective Activity of Artichoke (Cynara scolymus L.) Leaves Extract against High Fat Diet-Induced Obesity in Rats

Table 2

The inhibitory capacity of C. scolymus leaves extracts against lipase pancreatic activity.

Concentration (ug/ml)% InhibitionCI50 (ug/ml)

Orlistat2580.25 ± 1.0817.76
5097.21 ± 0.59
10090.35 ± 1.20

Hexane2517.46 ± 0.05200.15
5020.13 ± 1.19
10049.81 ± 0.28

Ethylacetate25--
50
100

Butanol2523.09 ± 1.88101.50
5030.13± 1.02
10070.18 ± 0.07

Ethanol2560.38 ± 1.5861.50
5069.23 ± 0.84
10073.90 ± 1.77

Aqueous2536.81 ± 0.0795.78
5062.10 ± 1.02
10067.24 ± 0.13

All data are expressed as mean ± SD. (-): inactive.