|
| Biological sample | Type of membrane | Conditions of separation | Performance indicator | References |
| Matrix | Functional group |
|
| (BSA) and (BHb) | poly(carbonate) | (i) Au
(ii) Carboxylic acid groups | (i) pH 4.7
(ii) Ionic strength: 0.01 M | (BSA/BHb) flux ratio: 67 | [74] |
|
| (BSA) and (BHb) | Anodic aluminum oxide (AAO) | - | (i) pH 4.7
(ii) Ionic strength: 0.01 M | (i) High selectivity: > 42
(ii) High throughput: > 10−8 Mcm−2 s−1 | [77] |
|
| Lysozyme/myoglobin | Mesoporous silica (SBA-15) | - | (i) pH 3.8
(ii) pH 4.5
(iii) pH 10.6 | (i) Lysozyme (pH 3.8): 6 µmol/g
(ii) Myoglobin (pH 4.5): 11 µmol/g
(iii) Lysozyme (pH 10.6): 11 µmol/g | [78] |
|
| Myoglobin | Polymer mixture of PCGF, PEI and PLGA | - | pH 5
pH 7
pH 9 | Transport rate across membrane (g m−2 h−1)
0.27
0.42
0.51 | [79] |
|
| Cytochrome C | Polymer mixture of PCGF, PEI and PLGA | - | pH 5
pH 7
pH 9 | Transport rate across membrane (g m−2 h−1)
0.38
0.58
0.54 | [79] |
|
| Proteins in urine | polycarbonate | - | 100 mM TBE buffer, pH 8.5 with 0.5% hydroxypropyl methyl cellulose (HPMC) | (i) Linear range of 0−100 μg mL−1
(ii) LOD: 1.5 μg mL−1,
(iii) HSA recovery: 81.2−116.8%. | [80] |
|
| Glycine, l-alanine, l-serine, l-glutamine, and l-lysine | porous alumina | poly(styrene sulfonate)/poly(allylamine hydrochloride) (PSS/PAH) | (i) 4.8 bar
(ii) 0.001 M
(iii) 18 mL/min | selectivity of glycine over l-glutamine: 50
flux: 1.3m3/(m2 day) | [81] |
|
| L-glutamine/glutamate | Polymer | - | (i) pH 7
(ii) 16 bar | (i) > 90% rejections of glutamate and nearly 85% passage of l-glutamine.
(ii) l-glutamine/glutamate selectivity: 21.7 flux: 0.81m3/(m2 day) | [82] |
|
