Research Article
Plasma miR-22-5p, miR-132-5p, and miR-150-3p Are Associated with Acute Myocardial Infarction
Table 1
Clinical characteristics of the AMI patients and control subjects in the first cohort.
| | Variable | AMI group | Control group | p-value | | (n = 35) | (n = 55) |
| | Male/Female (n/n) | 15/20 | 27/28 | 0.26 | | Age (years) | 60.86 ± 11.25 | 56.36 ± 12.36 | 0.09 | | Body mass index (kg/m2) | 25.43 ± 2.82 | 24.52 ± 2.52 | 0.12 | | Smoking status | | | | | Current smoker (%) | 6 (17%) | 4 (7%) | 0.15 | | Former smoker (%) | 12 (34%) | 11 (20%) | 0.13 | | Hypertension, n (%) | 11 (31%) | 12 (22%) | 0.31 | | Hyperlipidaemia, n (%) | 13 (37%) | 14 (25%) | 0.24 | | Diabetes mellitus, n (%) | 5 (14%) | 6 (11%) | 0.63 | | WBC (x 109 /L) | 9.35 ± 1.05 | 5.84 ± 1.28 | <0.01 | | SBP (mmHg) | 129.01 ± 15.32 | 128.52 ± 10.69 | 0.09 | | DBP (mmHg) | 74.21 ± 6.59 | 76.90 ± 7.87 | 0.10 | | Heart rate (beats/minutes) | 75.42 ± 12.57 | 74.05 ± 12.05 | 0.61 | | TC (mmol/L) | 4.84 ± 0.73 | 4.46 ± 1.09 | 0.07 | | HDL (mmol/L) | 1.37 ± 0.17 | 1.39 ± 0.19 | 0.61 | | LDL (mmol/L) | 3.13 ± 0.55 | 2.93 ± 0.68 | 0.15 | | TG (mmol/L) | 1.64 ± 0.69 | 1.71 ± 0.75 | 0.66 | | Cr (umol/L) | 74.27 ± 15.02 | 71.28 ± 10.96 | 0.28 | | CK-MB (IU/L) | 195.67 ± 63.20 | 8.56 ± 1.87 | <0.01 | | Medications | | | | | ACE inhibitors (%) | 22 (63%) | 8 (15%) | <0.01 | | Beta-blockers (%) | 27 (77%) | 6 (11%) | <0.01 | | Nitrates (%) | 25 (71%) | / | <0.01 | | Statins (%) | 35 (100%) | 14 (25%) | <0.01 | | Aspirin (%) | 35 (100%) | 8 (15%) | <0.01 | | Clopidogrel (%) | 35 (100%) | / | <0.01 |
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Data are shown as the mean ± SD, p<0.05, p<0.01 versus control subjects. |
