Research Article
Plasma miR-22-5p, miR-132-5p, and miR-150-3p Are Associated with Acute Myocardial Infarction
Table 2
Clinical characteristics of the enrolled subjects in the second cohort.
| Variable | Medication group | Control group | p-value | (n = 40) | (n = 50) |
| Male/Female (n/n) | 17/23 | 20/30 | 0.24 | Age (years) | 50.86 ± 12.30 | 46.36 ± 10.25 | 0.06 | Body mass index (kg/m2) | 24.31 ± 2.34 | 23.74 ± 1.95 | 0.21 | Smoking status | | | | Current smoker (%) | 6 (15%) | 4 (8%) | 0.33 | Former smoker (%) | 7 (18%) | 4 (8%) | 0.17 | Hypertension history, n (%) | 17 (43%) | 8 (16%) | <0.01 | Hyperlipidaemia history, n (%) | 25 (63%) | 7 (14%) | <0.01 | Diabetes mellitus, n (%) | 4 (10%) | 3 (6%) | 0.70 | WBC (x 109 /L) | 5.75 ± 1.15 | 5.64 ± 1.24 | 0.67 | Heart rate (beats/minutes) | 72.42 ± 10.86 | 75.05 ± 9.62 | 0.23 | Cr (umol/L) | 73.25 ± 14.38 | 69.72 ± 13.40 | 0.23 | Medications | | | | ACE inhibitors (%) | 14 (35%) | 5 (10%) | <0.01 | Beta-blockers (%) | 11 (28%) | 3 (6%) | <0.01 | Nitrates (%) | 5 (13%) | / | <0.01 | Statins (%) | 25 (63%) | 7 (14%) | <0.01 | Aspirin (%) | 10 (25%) | 3 (6%) | 0.02 | Clopidogrel (%) | 6 (15%) | / | <0.01 |
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Data are shown as the mean ± SD, p<0.05, p<0.01 patients for medications versus control subjects. |