Research Article

Plasma miR-22-5p, miR-132-5p, and miR-150-3p Are Associated with Acute Myocardial Infarction

Table 2

Clinical characteristics of the enrolled subjects in the second cohort.

VariableMedication groupControl groupp-value
(n = 40)(n = 50)

Male/Female (n/n)17/2320/300.24
Age (years)50.86 ± 12.3046.36 ± 10.250.06
Body mass index (kg/m2)24.31 ± 2.3423.74 ± 1.950.21
Smoking status
 Current smoker (%)6 (15%)4 (8%)0.33
 Former smoker (%)7 (18%)4 (8%)0.17
Hypertension history, n (%)17 (43%)8 (16%)<0.01
Hyperlipidaemia history, n (%)25 (63%)7 (14%)<0.01
Diabetes mellitus, n (%)4 (10%)3 (6%)0.70
WBC (x 109 /L)5.75 ± 1.155.64 ± 1.240.67
Heart rate (beats/minutes)72.42 ± 10.8675.05 ± 9.620.23
Cr (umol/L)73.25 ± 14.3869.72 ± 13.400.23
Medications
 ACE inhibitors (%)14 (35%)5 (10%)<0.01
 Beta-blockers (%)11 (28%)3 (6%)<0.01
 Nitrates (%)5 (13%)/<0.01
 Statins (%)25 (63%)7 (14%)<0.01
 Aspirin (%)10 (25%)3 (6%)0.02
 Clopidogrel (%)6 (15%)/<0.01

Data are shown as the mean ± SD, p<0.05, p<0.01 patients for medications versus control subjects.