Clinicopathologic Study of Calcifying Fibrous Tumor Emphasizing Different Anatomical Distribution and Favorable Prognosis
Figure 2
Histologic features of CFT. Spindle cells are embedded in the hyalinized stroma with prominent chronic inflammation and calcification (a; ×100); moderate power shows psammomatous calcification (arrowhead) and abundant plasma cells; Russell’s bodies either inside or outside of plasmacytes are frequently appreciable (arrow) (b, ×200); prominent hyalinized stroma results in the paucity of tumor cells and lymphoplasmacytic reaction; note the well-circumscribed border and compressed lung tissues in the lower side of this figure (c; ×50); dystrophic calcification is not uncommon (d; ×200); CFT involves liver; note the well-defined border against the normal hepatic tissue (left side) and the coexisting moderate to low differentiated hepatic carcinoma in other region (inset) (e; ×100); CFT juxtaposes Castleman’s disease (lower side) characterized by increased regressed lymphoid follicles and scattered tiny calcifications (f; ×100).