Diagnosis of Parapneumonia Pleural Effusion with Serum and Pleural Fluid Cell-Free DNA

Table 2

Serum and pleural effusion laboratory data of parapneumonic and nonparapneumonic pleural effusion patients.

	Non-parapneumonic effusion	Parapneumonic effusion	P value
	n=16	n=22
Serum level
White blood cell count (×10^9/L)	9.8(4.9, 14.2)	15.7(11.5, 19.4)
Neutrophil (%)	79.5(62.2, 82.2)	81.2(72.9, 86.1)
C reactive protein (mg/L)	75.0(12.7, 125.5)	177.6(129.9, 264.6)	<0.00
Procalcitonin (ng/mL)	0.18(0.09, 1.09)	0.92(0.27, 3.94)
LDH (U/L)	227.0(208.0, 248.0)	221.0(180.8, 271.0)
nucleus (ng/mL)	38.6(23.2, 73.7)	125.5(60.0, 281.3)
mitochondria (ng/mL)	21.2(15.0, 36.8)	31.8(14.5, 126.0)
Pleural fluid
White blood cell count (×10^6/L)	0.37(0.14, 0.95)	2.90(1.35, 11.01)	<0.00
Neutrophil (%)	8.0(3.5, 23.8)	84.0(60.0, 89.0)	<0.00
pH level	8.0(7.9, 8.3)	7.0(6.8, 8.1)
LDH (U/L)	92.5(72.5, 415.5)	1035.5(593.0, 2645.8)	<0.00
nucleus DNA (ng/mL)	1.8 (0.2, 59.1)	10300.0(1420.0, 14200.0)	<0.00
mitochondria DNA (ng/mL)	1.8(1.1, 13.7)	243.0(95.7, 491.5)	<0.00

LDH: lactic dehydrogenase; DNA: deoxyribonucleic acid.
Data was expressed as median (interquartile range Q1, Q3).
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