Serum Tumour Markers in Testicular Germ Cell Tumours: Frequencies of Elevated Levels and Extents of Marker Elevation Are Significantly Associated with Clinical Parameters and with Response to Treatment

Table 11

Tumour marker elevation rates in nonseminoma patients – synopsis of studies.

First author	year	n	AFP (%)	bHCG (%)	AFP or bHCG (%)	AFP and bHCG (%)
Szymendera [17]	1983	113	53.1	58.4
Nørgaard-Petersen [18]	1984	296	52.4	31.1	60	23
Fossa [19]	1987	95			70.5
Bassoulet [20]	1988	95	66	55	80	43
Fargeot [21]	1989	111	64.0	53.6
Kausitz [22]	1992	205	72.7	30.2	79.0	23.9
Javadpour [23]	1992	226	65.0	56.2	84.1
Kulkarni [24]	1993	166			68.7
Germa-Lluch [25]	2002	852	70.0	52.9		44.0
Neumann [26]	2011	73	66.7
Rothermundt [27]	2018	107	55.1	55.1
Dieckmann [28]	2019	187	59.7	63.6	78