(a)
(b)
(c)
(d)
(e)

Figure 3: Effects of high glucose on the odonto/osteogenic differentiation of SCAPs. (a, b) The expression of odonto/osteogenic genes (ALP, RUNX2, OSX, OCN, and DSPP) in 25 mmol/L high glucose-treated SCAPs was significantly higher than that in 5 mmol/L group at days 3 and 7. GAPDH served as an internal control. Values were presented as meansĀ± SD, n = 6. P < 0.01. (c) Western blot showed the odonto/osteogenic proteins (e.g., ALP, RUNX2, OSX, OCN, and DSP) in 25 mmol/L group were significantly higher than those in 5 mmol/L group at days 3 and 7. ACTIN served as an internal control. (d) Grayscale analysis of panel C. P < 0.05; P < 0.01.