BioMed Research International / 2019 / Article / Tab 2

Research Article

Prepregnancy Obesity, Maternal Dietary Intake, and Oxidative Stress Biomarkers in the Fetomaternal Unit

Table 2

Bivariate relation between oxidative stress markers and characteristics of the studied population.

VariableMaternal serum MDA
(µmol/L)
β (95% CI)
Cord serum MDA
(µmol/L)
β (95% CI)
Maternal serum TAC
(nmol/µl/µg protein)
β (95% CI)
Cord serum
TAC
(nmol/µl/µg protein)
β (95% CI)
GPx4
(Log A.U.O.D.)
β (95% CI)

Pre-pregnancy BMI (kg/m2)-0.0020.0009-0.01-0.004-0.01
(-0.02, 0.02)(-0.01, 0.01)(-0.06, 0.04)(-0.07, 0.06)(-0.03, 0.001)
Gestational age (weeks)0.080.04-0.01-0.15-0.07
(0.02, 0.13)(0.01, 0.08)(-0.20, 0.18)(-0.40, 0.10)(-0.11, -0.03)
Type of delivery (partum vs c-section)-0.09-0.04-0.200.22-0.10
(-0.31, 0.13)(-0.18, 0.10)(-0.86, 0.47)(-0.69, 1.13)(-0.27, 0.08)
Passive smoking0.100.05-0.09-1.10-0.07
(-0.18, 0.39)(-0.12, .23)(-0.87, 0.70)(-2.07, -0.13)(-0.28, 0.15)
Energy (per 1000 kcal)0.05-0.010.04-0.050.04
(-0.11, 0.22)(-0.12, 0.10)(-0.48, 0.56)(-0.75, 0.65)(-0.10, 0.17)
Proteins (g/100 kcal)0.110.010.19-0.050.03
(-0.07, 0.30)(-0.11, 0.13)(-0.35, 0.73)(-0.78, 0.69)(-0.12, 0.18)
Fats (g/100 kcal)-0.04-0.010.020.060.02
(-0.19, 0.11)(-0.11, 0.09)(-0.45, 0.49)(-0.55, 0.66)(-0.15, 0.11)
Iron (mg/100 kcal)0.310.210.38-0.770.02
(-0.01, 0.64)(0.00, 0.42)(-0.63, 1.40)(-2.15, 0.62)(-0.27, 0.30)
Magnesium (mg/100 kcal)-0.0003-0.01-0.04-0.050.005
(-0.04, 0.04)(-0.03, 0.01)(-0.16, 0.08)(-0.20, 0.10)(-0.02, 0.03)
Zinc (mg/100 kcal)0.80-0.032.330.15-0.61
(-0.21, 1.80)(-0.70, 0.63)(-0.76, 5.42)(-3.88, 4.17)(-1.45, 0.23)
Vitamin A (µg/100 kcal)0.00050.01-0.010.005-0.002
(-0.007, 0.008)(0.001, 0.01)(-0.03, 0.009)(-0.02, 0.03)(-0.008, 0.004)
Vitamin C (mg/100 kcal)0.020.020.010.010.003
(0.001, 0.05)(0.01, 0.03)(-0.70, 0.1)(-0.10, 0.11)(-0.02, 0.02)
Vitamin E (mg/100 kcal)-0.08-0.08-0.100.560.18
(-0.40, 0.24)(-0.34, 0.17)(-1.10, 0.88)(-1.30, 2.41)(-0.07, 0.43)
Maternal TAC (nmol/µl/µg protein)0.050.04-0.32-0.01
(-0.08, 0.17)(-0.05, 0.012)(-0.21, 0.86)(-0.13, 0.10)
Maternal MDA (µM)-0.440.45-0.93-0.16
(0.26, 0.61)(-0.81, 1.71)(-2.52, 0.68)(-0.46, 0.14)
GPx4 (log UADO)--0.38--0.20-
(-0.66, -0.11)(-1.00, 0.60)

MDA: malondialdehyde; TAC: total antioxidant capacity (adjusted for serum proteins). GPx4: glutathione peroxidase 4, logarithm of arbitrary units of optical density.
p<0.05.