Differentiation of Bone Marrow Mesenchymal Stem Cells into Neural Lineage Cells Induced by bFGF-Chitosan Controlled Release System

Figure 7

The key factors (c-fos and ERK) in the MAPK signaling pathway were effected by FGFR1 in different coculture system. (a) Expression of the bFGF receptor FGFR1 at different time points. bFGF-chitosan vs. soluble bFGF or bFGF-chitosan vs. chitosan. (b) Expression of the transcription factor c-fos in the MAPK signaling pathway. bFGF-chitosan vs. soluble bFGF or bFGF-chitosan vs. chitosan. (c) Expression of the transcription factor ERK in the MAPK signaling pathway. bFGF-chitosan vs. soluble bFGF or bFGF-chitosan vs. chitosan. (d-f) WB and densitometry are used to measure expression of protein of the bFGF receptor FGFR1 and key factors (c-fos and ERK) at different time points. bFGF-chitosan vs. soluble bFGF or bFGF-chitosan vs. chitosan. Data represent the means ± SE.

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