Research Article
Effect of eNOS on Ischemic Postconditioning-Induced Autophagy against Ischemia/Reperfusion Injury in Mice
Figure 3
IPostC increased autophagy via eNOS-mediated signaling and promoted autophagy via eNOS in I/R injured hearts. (a) The expression of LC3 in the myocardium at 30 min of reperfusion. IPostC increased the ratio of LC3-II/LC3-I compared to I/R group, which was abolished by eNOS inhibitor L-NIO. (b) IPostC decreased p62 expression compared with the I/R group, which was abolished by eNOS inhibitor L-NIO. n=6 per group. versus Control; versus I/R; versus IPostC.
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