Evaluation of the Immunogenicity of a Vascular Graft Covered with Collagen Derived from the European Carp (<i>Cyprinus carpio</i>) and Bovine Collagen

<div>Mean cytokine levels (pg/ml) in supernatants of<i> in vitro</i> stimulated splenocytes of implanted (BOV, CYP) and control groups (SHAM) determined using an enzyme-linked immunosorbent assay (ELISA) 7 days (green bars) and 14 days (yellow bars) after surgery. Cultures of mouse splenocytes were incubated in supplemented RPMI 1640 medium alone (C, negative control), with pokeweed mitogen (PWM, positive control), with bovine and carp gel (gBOV or gCYP), and bovine and carp implant (iBOV or iCYP). After a 72-hour incubation, the cultures were centrifuged and cytokine expression was measured in supernatants. All differences are not significant.</div>

BioMed Research International

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Figure 3

Figure 3: Evaluation of the Immunogenicity of a Vascular Graft Covered with Collagen Derived from the European Carp (<i>Cyprinus carpio</i>) and Bovine Collagen 

Figure 3 | Evaluation of the Immunogenicity of a Vascular Graft Covered with Collagen Derived from the European Carp (Cyprinus carpio) and Bovine Collagen 