The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy

Table 1

The effects of resveratrol administration are partly dependent on the gut microbiota.

Animal model	Treatment	Alerted bacterial taxa	Biological effects	Reference
Kunming mice	High-fat diet	Increasing Lactobacillus and Bifidobacterium abundance; decreasing Enterococcus faecalis abundance	Anti-obesity effects	Qiao et al. [41]
Wistar rats	High-fat sucrose diet	Decreasing the abundance of Parabacteroides genus	Altering the mRNA expression of tight-junction proteins and inflammation-associated genes	Etxeberria et al. [90]
Fischer F344 rats	DSS	Increasing Lactobacillus and Bifidobacterium abundance; decreasing Enterococcus faecalis abundance	Protecting the colonic mucosa architecture and reducing systemic inflammation markers	Larrosa et al. [84]
Wistar rats	High-fat diet	Inhibiting the growth of Bacteroides and Desulfovibrionaceae sp.; enhancing the proportion of Blautia and Dorea in the Lachnospiraceae family	Reducing fasting blood glucose levels and increasing the HDL-c levels	Yang et al. [91]
C57BL/6J mice	Choline or Trimethylamine	Increasing the relative abundance of Bacteroides, Lactobacillus, Bifidobacterium, and Akkermansia; decreasing the relative abundance of Prevotella, uncultured Ruminococcaceae, Anaerotruncus, Alistipes, Helicobacter, and uncultured Peptococcaceae	Anti-atherosclerosis effects	Chen et al. [93]