PSO-LocBact: A Consensus Method for Optimizing Multiple Classifier Results for Predicting the Subcellular Localization of Bacterial Proteins

Table 1

Summary of predictors used in this work.

Predictor	Organism categories	Subcellular compartments predicted	URL	References
SOSUI-GramN	Gram-negative bacteria	Extracellular region, outer membrane, periplasm, inner membrane, and cytoplasm	http://harrier.nagahama-i-bio.ac.jp/sosui/sosuigramn/sosuigramn_submit.html	[1]
CELLO	Bacteria, eukaryotes	Extracellular region, outer membrane, inner membrane, periplasm, and cytoplasm	http://cello.life.nctu.edu.tw/	[2, 3]
CELLO2GO	Archaea, bacteria, eukaryotes, viruses	Extracellular region, outer membrane, inner membrane, periplasm, and cytoplasm	http://cello.life.nctu.edu.tw/cello2go/	[4]
PSLpred	Gram-negative bacteria	Extracellular region, outer membrane, inner membrane, periplasm, and cytoplasm	http://crdd.osdd.net/raghava/pslpred/	[5]
SLP-local	Prokaryotes, eukaryotes	3 locations for prokaryotes (cytoplasm, extracellular region, and periplasm)	http://sunflower.kuicr.kyoto-u.ac.jp/∼smatsuda/slplocal.html	[6]
Gneg-mPLoc	Gram-negative bacteria	Cytoplasm, extracellular region, fimbria, flagella, inner membrane, nucleoid, outer membrane, and periplasm	http://www.csbio.sjtu.edu.cn/bioinf/Gneg-multi/	[7, 8]
Gpos-mPLoc	Gram-positive bacteria	Cytoplasm, cell wall, plasma membrane, and extracellular region	http://www.csbio.sjtu.edu.cn/bioinf/Gpos-multi/	[8, 9]
PSORTb 3.0	Archaea, bacteria	4 locations for Gram-positive bacteria and archaea (cytoplasm, cytoplasmic membrane, cell wall, and extracellular region)	http://www.psort.org/psortb	[10]
		5 locations for Gram-negative bacteria (cytoplasm, inner membrane, periplasm, outer membrane, and extracellular region)
ngLOC	Prokaryotes, eukaryotes	4 locations for Gram-positive bacteria (cytoplasm, inner membrane, cell wall, and extracellular region)	http://genome.unmc.edu/ngLOC/index.html	[11]
		5 locations for Gram-negative bacteria (cytoplasm, inner membrane, periplasm, outer membrane, and extracellular region)
LocTree3	Archaea, bacteria, eukaryotes	3 locations for archaea (cytoplasm, extracellular region, and plasma membrane)	https://rostlab.org/services/loctree3/	[12]
		6 locations for bacteria (cytoplasm, extracellular region, fimbria, outer membrane, periplasm, and plasma membrane)