Significance of the Differential Peptidome in Multidrug-Resistant Tuberculosis

Figure 9

Inflammatory effects of differently expressed peptides (F2 and CR2: 1 μM, 10 μM, and 100 μM) to THP-1 cells. (a) IL-1β mRNA expression did not change after the addition of F2 and CR2. (b) TNFα mRNA expression did not change after the addition of F2 and CR2. (c) IL-6 mRNA expression significantly decreased after the addition of CR2 (P < 0.05; P < 0.01), but there was no change after the addition of F2. (d) IL-8 mRNA expression did not change after the addition of F2 and CR2 (N: negative control; I+L: LPS and r-IFN).

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