Splenectomy Promotes Macrophage Polarization in a Mouse Model of Concanavalin A- (ConA-) Induced Liver Fibrosis

Figure 4

F4/80⁺ macrophages and F4/80⁺ inducible nitric oxide synthase (NOS)⁺ macrophages were detected by (a) immunofluorescent staining and (b) the ratios were calculated. The M2 macrophage-related cytokines (c) interleukin- (IL-) 10, arginase- (ARG-) 1, and IL-4 were detected by RT-PCR. ConA, concanavalin A; DEX, dexamethasone. indicates P < 0.001.

(a)

(b)

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