Application of Aluminum Oxide Nanoparticles in<i> Aspergillus terreus</i> Cultivations: Evaluating the Effects on Lovastatin Production and Fungal Morphology

<div>Time courses of lovastatin (a), biomass (b), and lactose (c) concentration in shake flask cultures of<i> Aspergillus terreus</i> ATCC 20542 propagated with aluminum oxide (Al<sub>2</sub>O<sub>3</sub>) micro- and nanoparticles at the concentration of 6 and 12 g <span class="nowrap"><svg height="11.6047pt" id="M22" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.5549 10.2382 11.6047" width="10.2382pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M238 0V26C174 32 166 38 166 104V712C132 700 70 683 18 677V653C81 647 87 645 87 577V104C87 38 78 32 15 26V0H238Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,3.289,-5.741)"><path d="M300 253H71L57 198H286L300 253Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,6.529,-5.741)"><path d="M311 0V25C221 32 216 41 216 113V635C162 613 103 594 39 583V559L88 556C131 552 135 546 135 500V113C135 41 131 32 40 25V0H311Z"></path></g></svg>.</span> Cultivations performed without aluminum oxide served as experimental controls. All experiments were conducted in triplicate. Error bars represent the standard deviation values.</div>

BioMed Research International

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Figure 3: Application of Aluminum Oxide Nanoparticles in<i> Aspergillus terreus</i> Cultivations: Evaluating the Effects on Lovastatin Production and Fungal Morphology 

Figure 3 | Application of Aluminum Oxide Nanoparticles in Aspergillus terreus Cultivations: Evaluating the Effects on Lovastatin Production and Fungal Morphology 