Research Article
Analysis of Synonymous Codon Usage Bias in Flaviviridae Virus
Table 2
Nucleotide contents in ORFs of 66 Flaviviridae virus genomes.
| virus strain | A | U | G | C | | | | | GC |
| Aedes flavivirus | 0.2528 | 0.2467 | 0.2621 | 0.2384 | 0.2991 | 0.2994 | 0.279 | 0.3412 | 0.501 | Alkhurma virus | 0.2436 | 0.2157 | 0.371 | 0.2237 | 0.2976 | 0.3617 | 0.2773 | 0.2729 | 0.553 | Apoi virus | 0.2763 | 0.2754 | 0.2754 | 0.2075 | 0.3367 | 0.3906 | 0.2441 | 0.2722 | 0.497 | Bagaza virus | 0.2916 | 0.2125 | 0.2929 | 0.2129 | 0.3307 | 0.3727 | 0.2501 | 0.2893 | 0.508 | Banzi virus | 0.2727 | 0.2232 | 0.2816 | 0.2225 | 0.3089 | 0.2731 | 0.3045 | 0.338 | 0.504 | Bouboui virus | 0.2889 | 0.2297 | 0.2698 | 0.2116 | 0.3351 | 0.3785 | 0.2452 | 0.2867 | 0.495 | Bussuquara virus | 0.2842 | 0.2174 | 0.283O | 0.2155 | 0.3601 | 0.2576 | 0.3067 | 0.3066 | 0.499 | Cell fusing agent virus | 0.2443 | 0.2459 | 0.2744 | 0.2355 | 0.3115 | 0.3796 | 0.2407 | 0.2843 | 0.522 | Chaoyang virus | 0.2901 | 0.225 | 0.2704 | 0.2126 | 0.33 | 0.3704 | 0.2491 | 0.3071 | 0.495 | Culex flavivirus | 0.2349 | 0.2357 | 0.2973 | 0.2321 | 0.2501 | 0.2545 | 0.397 | 0.3328 | 0.529 | Dengue virus 1 | 0.3191 | 0.2142 | 0.26 | 0.2087 | 0.3547 | 0.3652 | 0.234 | 0.3045 | 0.476 | Dengue virus 2 | 0.3317 | 0.2111 | 0.2529 | 0.2043 | 0.4714 | 0.2334 | 0.2451 | 0.2871 | 0.457 | Dengue virus 3 | 0.3219 | 0.2141 | 0.2586 | 0.2053 | 0.4462 | 0.2457 | 0.2693 | 0.2763 | 0.464 | Dengue virus 4 | 0.3105 | 0.2201 | 0.2631 | 0.2063 | 0.4249 | 0.2473 | 0.2757 | 0.2825 | 0.47 | Donggang virus | 0.2707 | 0.245 | 0.2719 | 0.2124 | 0.3152 | 0.3769 | 0.2511 | 0.3051 | 0.501 | Edge Hill virus | 0.2847 | 0.2389 | 0.2842 | 0.1921 | 0.3288 | 0.3993 | 0.2482 | 0.2822 | 0.491 | Entebbe bat virus | 0.2783 | 0.2159 | 0.2806 | 0.2252 | 0.3473 | 0.383 | 0.2352 | 0.279 | 0.516 | Gadgets Gully virus | 0.2624 | 0.2166 | 0.313 | 0.2079 | 0.2986 | 0.3771 | 0.2743 | 0.2757 | 0.532 | Hanko virus | 0.2691 | 0.2657 | 0.2632 | 0.2019 | 0.3305 | 0.3314 | 0.3091 | 0.2726 | 0.465 | Ilheus virus | 0.2689 | 0.2082 | 0.2797 | 0.2432 | 0.3231 | 0.3587 | 0.2462 | 0.3097 | 0.535 | Japanese encephalitis ORF | 0.2776 | 0.2082 | 0.2836 | 0.2306 | 0.3342 | 0.2401 | 0.2989 | 0.3489 | 0.516 | Jugra virus | 0.2901 | 0.2282 | 0.2698 | 0.2119 | 0.3328 | 0.3843 | 0.2382 | 0.2915 | 0.493 | Kadam virus | 0.2547 | 0.22 | 0.3107 | 0.2156 | 0.3057 | 0.3668 | 0.286 | 0.2733 | 0.539 | Kamiti River virus | 0.2514 | 0.2487 | 0.2659 | 0.234 | 0.3214 | 0.3984 | 0.2325 | 0.2717 | 0.511 | Karshi virus, | 0.2431 | 0.2135 | 0.3211 | 0.2222 | 0.3026 | 0.3702 | 0.2723 | 0.2739 | 0.555 | Kedougou virus | 0.2431 | 0.2135 | 0.3211 | 0.2222 | 0.2587 | 0.2401 | 0.3928 | 0.3261 | 0.544 | Kokobera virus | 0.2813 | 0.2252 | 0.2892 | 0.21 | 0.3492 | 0.2586 | 0.3173 | 0.3049 | 0.496 | Langat virus | 0.2447 | 0.212 | 0.3231 | 0.2202 | 0.2897 | 0.3706 | 0.2812 | 0.2773 | 0.555 | Louping ill virus | 0.2447 | 0.2072 | 0.3213 | 0.2267 | 0.2695 | 0.2319 | 0.3766 | 0.3314 | 0.548 | Meaban virus | 0.2444 | 0.2136 | 0.3308 | 0.2112 | 0.3005 | 0.3715 | 0.2927 | 0.2632 | 0.556 | Mercadeo virus | 0.2506 | 0.2437 | 0.2758 | 0.2299 | 0.2708 | 0.2793 | 0.3449 | 0.3498 | 0.506 | Modoc virus | 0.2962 | 0.2516 | 0.2713 | 0.1809 | 0.3502 | 0.4155 | 0.2285 | 0.2741 | 0.467 | Montana myotis leukoencephalitis virus | 0.2981 | 0.2634 | 0.2602 | 0.1783 | 0.3849 | 0.3809 | 0.2558 | 0.2181 | 0.439 | Mosquito flavivirus | 0.2384 | 0.2395 | 0.2781 | 0.2435 | 0.3186 | 0.385 | 0.2311 | 0.2708 | 0.534 | Murray Valley encephalitis virus | 0.2888 | 0.23 | 0.2748 | 0.2114 | 0.3319 | 0.3763 | 0.2476 | 0.3041 | 0.498 | New Mapoon virus | 0.2635 | 0.2213 | 0.2706 | 0.2446 | 0.3134 | 0.365 | 0.2549 | 0.2954 | 0.53 | Nounane virus | 0.2856 | 0.217 | 0.2725 | 0.2245 | 0.367 | 0.2474 | 0.2875 | 0.3315 | 0.497 | Ntaya virus | 0.2856 | 0.217 | 0.2725 | 0.2245 | 0.3326 | 0.3788 | 0.2503 | 0.2914 | 0.493 | Ochlerotatus caspius flavivirus | 0.2688 | 0.2588 | 0.2665 | 0.2059 | 0.3354 | 0.4017 | 0.2326 | 0.2797 | 0.483 | Omsk hemorrhagic fever virus | 0.2566 | 0.2082 | 0.3127 | 0.2224 | 0.3058 | 0.3668 | 0.2723 | 0.2706 | 0.545 | Palm Creek virus i | 0.2636 | 0.2411 | 0.2878 | 0.2075 | 0.344 | 0.263 | 0.3588 | 0.2686 | 0.495 | Paraiso Escondido virus | 0.2896 | 0.2355 | 0.2899 | 0.1851 | 0.3286 | 0.3904 | 0.2579 | 0.2847 | 0.487 | Parramatta River virus | 0.2671 | 0.2595 | 0.2642 | 0.2093 | 0.3359 | 0.3938 | 0.2329 | 0.2816 | 0.485 | Phnom Penh bat virus | 0.2871 | 0.2663 | 0.2716 | 0.1748 | 0.3384 | 0.4136 | 0.2593 | 0.2664 | 0.461 | Powassan virus | 0.2516 | 0.2157 | 0.3128 | 0.2198 | 0.3052 | 0.369 | 0.2753 | 0.2685 | 0.545 | Quang Binh virus | 0.2388 | 0.2385 | 0.2776 | 0.2451 | 0.2615 | 0.2645 | 0.3321 | 0.3681 | 0.523 | Rio Bravo virus | 0.3025 | 0.2656 | 0.2502 | 0.1817 | 0.4023 | 0.3798 | 0.2283 | 0.2363 | 0.432 | Saboya virus | 0.285 | 0.2385 | 0.2706 | 0.2059 | 0.3285 | 0.3872 | 0.2449 | 0.2944 | 0.492 | Saumarez Reef virus | 0.2511 | 0.215 | 0.3173 | 0.2166 | 0.2973 | 0.374 | 0.2959 | 0.267 | 0.548 | Sepik virus | 0.2899 | 0.2386 | 0.2638 | 0.2077 | 0.3407 | 0.3931 | 0.237 | 0.2877 | 0.483 | Spanish goat encephalitis virus | 0.2442 | 0.2081 | 0.3233 | 0.2244 | 0.2982 | 0.3667 | 0.2776 | 0.273 | 0.559 | Spondweni virus | 0.2442 | 0.2081 | 0.3233 | 0.2244 | 0.3183 | 0.3631 | 0.2483 | 0.3024 | 0.532 | St. Louis encephalitis virus | 0.2918 | 0.2116 | 0.2801 | 0.2165 | 0.3399 | 0.3721 | 0.2471 | 0.293 | 0.507 | Tamana bat virus | 0.3312 | 0.2839 | 0.2156 | 0.1692 | 0.4208 | 0.4285 | 0.1901 | 0.2618 | 0.402 | Tembusu virus | 0.2866 | 0.2238 | 0.2894 | 0.2002 | 0.3304 | 0.3717 | 0.2567 | 0.2909 | 0.503 | Tick-borne encephalitis virus | 0.247 | 0.212 | 0.3207 | 0.2202 | 0.3013 | 0.3668 | 0.2743 | 0.2765 | 0.552 | Uganda S virus | 0.247 | 0.21 | 0.3207 | 0.2202 | 0.3802 | 0.3114 | 0.2594 | 0.2795 | 0.469 | Usutu virus | 0.2707 | 0.2192 | 0.2819 | 0.2281 | 0.3117 | 0.2699 | 0.3012 | 0.3368 | 0.511 | Wesselsbron virus | 0.2856 | 0.2395 | 0.2665 | 0.2085 | 0.3406 | 0.3906 | 0.2345 | 0.2926 | 0.487 | West Nile virus lineage 1 | 0.2724 | 0.2155 | 0.2883 | 0.2238 | 0.3261 | 0.369 | 0.2552 | 0.2923 | 0.522 | West Nile virus lineage 2 | 0.2727 | 0.217O | 0.2827 | 0.2275 | 0.3141 | 0.2635 | 0.307 | 0.3417 | 0.51 | Yaounde virus | 0.2884 | 0.2068 | 0.2849 | 0.2199 | 0.3712 | 0.2188 | 0.3192 | 0.3227 | 0.505 | Yellow fever virus | 0.2704 | 0.2326 | 0.286 | 0.2109 | 0.3336 | 0.3969 | 0.2386 | 0.2839 | 0.509 | Yokose virus | 0.3003 | 0.2298 | 0.2597 | 0.2103 | 0.354 | 0.3887 | 0.2234 | 0.2839 | 0.483 | Zika virus | 0.2777 | 0.2146 | 0.2908 | 0.2169 | 0.3192 | 0.3704 | 0.2532 | 0.2952 | 0.52 | average value | 0.2732 | 0.2288 | 0.2849 | 0.21479 | 0.3310 | 0.3440 | 0.2705 | 0.2924 | 0.5052 | SD | 0.0236 | 0.0192 | 0.02532 | 0.0163 | 0.04052 | 0.0588 | 0.0410 | 0.02749 | 0.03233 |
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