Rare Mutations in AHDC1 in Patients with Obstructive Sleep Apnea

Table 1

Baseline characteristics of participants.

Measure	OSA group	Control group
Number of subjects	257	100	—
Age (years)	58.97 ± 9.41	58.11 ± 10.92	0.055
Sex (% male)	84.82	70.00	0.002
BMI (kg/m^2)	27.04 ± 3.36^#	23.71 ± 3.09	<0.001
TC (mmol/L)	4.13 ± 1.00	3.99 ± 1.02	0.569
TG (mmol/L)	1.56 ± 1.04^#	1.24 ± 0.36	0.002
HDL-C (mmol/L)	1.07 ± 0.23	1.00 ± 0.18	0.018
LDL-C (mmol/L)	2.47 ± 0.87^#	2.43 ± 0.83	0.400
GLU (mmol/L)	3.46 ± 0.95^#	3.44 ± 0.62	0.002
Hypertension (%)	22.96	13.00	0.035
AHI	32.17 ± 18.06^#	3.33 ± 1.14	<0.001
MSaO2 (%)	93.48 ± 2.28^#	95.00 ± 1.37 ^#	0.002
LSaO2 (%)	82.14 ± 9.89^#	90.00 ± 2.73	<0.001

Data are expressed as mean ± standard deviation or n (%). Differences between groups were analyzed by the independent Student’s t-test, chi-squared test, or Wilcoxon test. ^#Data were asymmetrically distributed. . BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; GLU: fasting blood glucose; AHI: apnea-hypopnea index; MSaO2: mean oxygen saturation; LSaO₂: lowest oxygen saturation.