Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury
SAA expression increases within injury severity. Correlation between the SAA levels in serum after 1 day after injury with the lesion score (a), cell death (b), microglia/macrophages (c), and neutrophil infiltration (d) was assessed. (e) Summary of secondary injury processes that trigger neuropathological and inflammatory responses and release into the bloodstream. Mild to severe injury causes lower to higher SAA levels, respectively.