Eliminating Risk of Intubation in Very Preterm Infants with Noninvasive Cardiorespiratory Support in the Delivery Room and Neonatal Intensive Care Unit
Table 2
Respiratory and pertinent NICU care processes.
Very preterm infants, < 33 weeks gestation
Extremely low birth weight infants, < 1000 g
Variable,
2008-2010
2011-2013
2014-2017
p
2008-2010
2011-2013
2014-2017
p
or Median (IQR)
Delivery room intubation
23
15
5
<0.001
64
40
19
<0.001
Invasive ventilation
37
30
17
<0.001
92
71
51
<0.001
Invasive ventilation, days
4 (1 - 20)
4 (1 - 13)
4.6 (2 - 16)
ns
18 (5 - 32)
9 (3 - 17)
15 (5 - 39)
ns
Non invasive mechanical ventilation (NIMV)
18
23
17
ns
58
65
65
ns
NIMV, days
6 (3 - 15)
10 (2 - 17)
9 (2 - 24)
ns
8 (4 - 25)
10 (5 - 21)
19 (4 - 27)
ns
Continuous positive airway pressure (CPAP)
78
78
84
ns
89
83
81
ns
CPAP, days
4 (2 - 19)
4 (2 - 16)
7 (2 - 21)
0.004
22 (5 - 39)
25 (10 - 43)
30 (16 - 40)
ns
Surfactant
27
18
20
0.042
74
40
43
0.001
Caffeine
48
58
69
<0.001
85
94
97
ns
Vitamin A
15
1
13
<0.001
58
2
46
<0.001
Post natal steroids
10
7
3
0.01
43
23
16
0.01
Colostrum within 24 hours
45
76
86
<0.01
38
72
84
<0.001
Infant antibiotics
67
59
41
<0.01
96
90
73
0.004
Statistically significant difference between 2008-2010 and 2011-2013. Statistically significant difference between 2008-2010 and 2014-2017. Statistically significant difference between 2011-2013 and 2014-2017. Data summarized for those infants who received invasive ventilation, NIMV, CPAP, and nasal cannula.
