FBW7 Regulates the Autophagy Signal in Mesangial Cells Induced by High Glucose

Figure 1

The expression of FBW7 protein and mRNA in renal mesangial cells induced by different concentrations of glucose for 48h. (a) FBW7 protein in renal mesangial cells induced by different concentrations of glucose and detected by western blot. (c) FBW7 mRNA detected by RT-PCR for different concentrations of glucose. (b, d) The corresponding relative gray value statistics graph of FBW7 level. NC group was treated with 5.6mmol/L glucose. OP group was treated with 5.6mmol/L glucose and 24.4mmol/L mannitol. HG1 group was treated with 10 mmol/L glucoses. HG2 group was treated with 20 mmol/L glucoses. HG3 group was treated with 30 mmol/L glucoses. P < 0.05 and P < 0.01.

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