FBW7 Regulates the Autophagy Signal in Mesangial Cells Induced by High Glucose

Figure 2

Effects of 30 mmol/L high glucose and rapamycin on mTOR/autophagy signaling in renal mesangial cells. (a) Autolysosome detected by confocal laser scanning microscope. (b) Quantitative analyses of number of autolysosomes. (c) mTOR, p-mTOR, and LC3-II/I detected by western blot. (d) The corresponding relative gray value statistics graph of LC3B. (e) The corresponding relative gray value statistics graph of p-mTOR/mTOR. P < 0.05 and P < 0.01.

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