Tumor Mutational Burden and Genomic Alterations in Chinese Small Cell Lung Cancer Measured by Whole-Exome Sequencing

<div>Genomic alterations in the 20 patients of the current study. (a) The base substitution fractions. Five cases on the left side are nonsmokers, the other fifteen patients are smokers. (b) The TMB values of those patients, where blue bars indicate nonsmokers and red bars indicate smokers. (c) An overview of significantly mutated genes. Genes were listed top down according to aberration frequencies. (d) Significantly amplified genes.</div>

BioMed Research International

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Figure 1

Figure 1: Tumor Mutational Burden and Genomic Alterations in Chinese Small Cell Lung Cancer Measured by Whole-Exome Sequencing 