Research Article

Translational Difficulties in Querying Rats on “Orientation”

Figure 11

Escape latency (mean ± SEM) of the 1st trials (both in the morning and in the evening) in the 2-platform+closed board experiment of 18 Long–Evans rats (black solid curve, filled symbols, left Y-axis), and of the 2nd trials (morning, evening) (gray solid curve, unfilled symbols, left Y-axis). On training days 6–17 only escape latencies of rats that found the platform were considered. Orange dashed line and filled circle symbols show the mean rank ± SEM of visits to the actual target zone out of the two possible locations in trial 1 and green dashed line with unfilled circle symbols represent rank ± SEM in trial 2 (right Y-axis). Rank 1 represents the choice of swimming directly to target, rank 2 represents the choice of swimming to the wrong direction; rank 1.5 (blue dashed line) indicates chance level.