Gastric Mucosal Lesions in Tibetans with High-Altitude Polycythemia Show Increased HIF-1A Expression and ROS Production

Figure 2

HE staining comparison for gastric biopsy between HAPC patients and healthy controls. (a) For the gastric biopsy from healthy controls, the duct is in normal structure with suitable amounts of blood vessels and red blood cells; (b) for the gastric biopsy from HAPC patients, the duct is destroyed. A large number of red blood cells were gathered in gastric vessels. Parietal cells are overproliferated in gastric biopsies. The number of gastric cells is decreased while the diameter of gastric mucosal vessels is increased compared with healthy controls. (c) Microvessel density (MVD). (d) Average diameter of gastric mucosal vessels. p < 0.05 via controls.

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